Catechin-13C3

Catechin-13C3 is the 13C-labeled Catechin. Catechin ((+) -Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

Product Specifications

Product Name Alternative

(+) -Catechin-13C3; Cianidanol-13C3; Catechuic acid-13C3

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Apoptosis; COX; Endogenous Metabolite; Influenza Virus

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/catechin-13c3.html

Purity

98.06

Solubility

10 mM in DMSO

Smiles

O[13C@@]1[13C@@](C2=CC(O)=C(O)C=C2)OC3=CC(O)=CC(O)=C3[13C]1

Molecular Formula

C12 13C3H14O6

Molecular Weight

293.25

Precautions

H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40 (2) :173-9.|[3]Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.|[4]Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70 (1) :245-259.