2-Hydrazinobenzothiazole
2-Hydrazinobenzothiazole is a potent IDO1 inhibitor with an IC50 of 8 μM. 2-hydrazinobenzothiazole interacts with the IDO1 haem through hydrazine. 2-hydrazinobenzothiazole has the potential for immune system related diseases research[1].
Product Specifications
CAS Number
615-21-4
UNSPSC
12352005
Hazard Statement
H301, H315, H319
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-hydrazinobenzothiazole.html
Purity
99.95
Solubility
DMSO : ≥ 100 mg/mL
Smiles
NNC1=NC2=CC=CC=C2S1
Molecular Formula
C7H7N3S
Molecular Weight
165.22
Precautions
H301, H315, H319
References & Citations
[1]Sai-Parng S Fung, et al. Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1) . Bioorg Med Chem. 2013 Dec 15;21 (24) :7595-603.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1
Available Sizes
Frequently Asked Questions
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