Flt2-11

Flt2-11 is a anti-angiogenic peptide, and specifically binds NRP-1. Flt2-11 inhibits NRP-1/sVEGFR-1 interaction.

Product Specifications

CAS Number

[329189-44-8]

UNSPSC

12352209

Target

VEGFR

Type

Peptides

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/flt2-11.html

Purity

99.71

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(N)=O)N

Molecular Formula

C61H104N14O15

Molecular Weight

1273.56

References & Citations

[1]Colotti G, et al. Neuropilin-1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1. FEBS J. 2022;289 (1) :183-198.