Anditixafortide
Anditixafortide (Pentixather) is an endoradiotherapeutic vector. Anditixafortide is a CXCR4-targeting peptide derivative[1]. Anditixafortide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
Product Specifications
CAS Number
1821136-83-7
UNSPSC
12352209
Target
CXCR; Radionuclide-Drug Conjugates (RDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; GPCR/G Protein; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anditixafortide.html
Purity
99.27
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@H](N(C([C@H](NC(CNC1=O)=O)CC2=CC(I)=C(C=C2)O)=O)C)CCCNC(C3=CC=C(C=C3)CNC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)=O)CCCNC(N)=N)N[C@H]1CC5=CC6=C(C=CC=C6)C=C5
Molecular Formula
C60H79IN14O14
Molecular Weight
1347.26
References & Citations
[1]Nicolas Lepareur, et al. Clinical Advances and Perspectives in Targeted Radionuclide Therapy. Pharmaceutics. 223, 15, 6.|[2]Ken Herrmann, et al. First-in-Human Experience of CXCR4-Directed Endoradiotherapy with 177Lu- and 90Y-Labeled Pentixather in Advanced-Stage Multiple Myeloma with Extensive Intra- and Extramedullary Disease. J Nucl Med. 2016, 57, 2.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
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Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
RDC Peptide
Available Sizes
Frequently Asked Questions
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