Α-Defensin-6 (Human)

<strong>Œ±-Defensin-6 (Human)</strong>_x000D_ <b>Catalog number: </b>MDP0816_x000D_ <strong>Amount:</strong> 0.1 mg_x000D_ <b>Name:</b> Ala-Phe-Thr-Cys-His-Cys-Arg-Arg-Ser-Cys-Tyr-Ser-Thr-Glu-Tyr-Ser-Tyr-Gly-Thr-Cys-Thr-Val-Met-Gly-Ile-Asn-His-Arg-Phe-Cys-Cys-Leu (Disulfide bonds between Cys4-Cys31, Cys6-Cys20, and Cys10-Cys30)_x000D_ <b>Other name(s): </b>Œ±-Defensin-6 (Human)_x000D_ <b>Molecular Formula: </b>C₁₅₆H₂₂₈N₄₆O₄₆S₇_x000D_ <b>Molecular Mass: </b>3708.2 g/mol_x000D_ <b>CAS #: </b>N/A_x000D_ <b>Storage Temperature: </b>-20‚ÑÉ_x000D_ <b> </b>_x000D_ <strong>References:</strong>_x000D_ 1: Hayashi R, Tsuchiya K, Fukushima K, Horita N, Hibiya S, Kitagaki K, Negi M, Itoh E, Akashi T, Eishi Y, Okada E, Araki A, Ohtsuka K, Fukuda S, Ohno H, Okamoto R, Nakamura T, Tanaka S, Chayama K, Watanabe M. Reduced Human Œ±-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease Inflamm Bowel Dis. 2016 May;22(5):1119-28._x000D_ 2: Chakraborty S, Chatterjee R, Chakravortty D. Evolving and assembling to pierce through: Evolutionary and structural aspects of antimicrobial peptides Comput Struct Biotechnol J. 2022 May 10;20:2247-2258._x000D_ 3: Wang A, Su Y, Wang S, Shen M, Chen F, Chen M, Ran X, Cheng T, Wang J. High efficiency preparation of bioactive human alpha-defensin 6 in Escherichia coli Origami(DE3)pLysS by soluble fusion expression Appl Microbiol Biotechnol. 2010 Aug;87(5):1935-42._x000D_ 4: Mathew B, Nagaraj R. Antimicrobial activity of human Œ±-defensin 6 analogs: insights into the physico-chemical reasons behind weak bactericidal activity of HD6 in vitro J Pept Sci. 2015 Nov;21(11):811-8._x000D_ 5: Wyatt MC, Beswick AD, Kunutsor SK, Wilson MJ, Whitehouse MR, Blom AW. The Alpha-Defensin Immunoassay and Leukocyte Esterase Colorimetric Strip Test for the Diagnosis of Periprosthetic Infection: A Systematic Review and Meta-Analysis J Bone Joint Surg Am. 2016 Jun 15;98(12):992-1000._x000D_ 6: Tang Y, Zhang D, Gong X, Zheng J. Repurposing of intestinal defensins as multi-target, dual-function amyloid inhibitors via cross-seeding Chem Sci. 2022 May 20;13(24):7143-7156._x000D_ 7: Su X, Jin M, Xu C, Gao Y, Yang Y, Qi H, Zhang Q, Yang X, Ya W, Zhang Y, Yang R. FABP4 in Paneth cells regulates antimicrobial protein expression to reprogram gut microbiota Gut Microbes. 2022 Jan-Dec;14(1):2139978._x000D_ 8: Li X, Ma H, Sun Y, Li T, Wang C, Zheng H, Chen G, Du G, Ji G, Yang H, Xiao W, Qiu Y. Effects of fecal stream deprivation on human intestinal barrier after loop ileostomy J Gastroenterol Hepatol. 2022 Jun;37(6):1119-1130._x000D_ 9: Pereira NS, Queiroga TBD, da Silva DD, Nascimento MSL, Andrade CM, Souto JT, Ricci MF, Arantes RME, Zamboni DS, Chiari E, C√¢mara ACJD, Galv√£o LMDC, Guedes PMM. NOD2 receptor is crucial for protecting against the digestive form of Chagas disease PLoS Negl Trop Dis. 2020 Sep 28;14(9):e0008667._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11527925">10: Paulsen FP, Pufe T, Schaudig U, Held-Feindt J, Lehmann J, Schr√∂der JM, Tillmann BN. Detection of natural peptide antibiotics in human nasolacrimal ducts Invest Ophthalmol Vis Sci. 2001 Sep;42(10):2157-63.</a>_x000D_ _x000D_ <strong>Products Related to Œ±-Defensin-6 (Human) can be found at</strong> <a href="https://moleculardepot.com/product-category/peptides/">Peptides</a>