Anti-osteoporosis agent-9

Anti-osteoporosis agent-9 (compound 5b) is a N-cyclopropyl-4- ((4- ((4- (trifluoromethyl) phenyl) sulfonyl) piperazin-1-yl) methyl) benzamide derivative that shows anti-osteoclast activity[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Cathepsin; MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-osteoporosis-agent-9.html

Smiles

O=C(C1=CC=C(C=C1)CN2CCN(CC2)S(=O)(C3=CC=C(C=C3)C(F)(F)F)=O)NC4CC4

Molecular Formula

C22H24F3N3O3S

Molecular Weight

467.50

References & Citations

[1]Marie Encarnacion A, et al. Novel inhibitor N-cyclopropyl-4- ((4- ((4- (trifluoromethyl) phenyl) sulfonyl) piperazin-1-yl) methyl) benzamide attenuates RANKL-mediated osteoclast differentiation in vitro. Bioorg Med Chem Lett. 2024;110:129884.