Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Cynaropicrin (Standard)

Cynaropicrin (Standard) is the analytical standard of Cynaropicrin. This product is intended for research and analytical applications. Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.

Product Specifications

CAS Number

35730-78-0

UNSPSC

12352005

Target

MMP; NF-κB; Reference Standards; TNF Receptor

Type

Reference Standards

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cynaropicrin-standard.html

Smiles

C=C([C@H]1O)[C@]([C@@]2([H])C1)([H])[C@](OC3=O)([H])[C@@](C3=C)([H])[C@@H](OC(C(CO)=C)=O)CC2=C

Molecular Formula

C19H22O6

Molecular Weight

346.37

References & Citations

[1]Cho JY, et al. In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa. Eur J Pharmacol. 2000 Jun 23;398 (3) :399-407.|[2]Masutani T, et al. Cynaropicrin is dual regulator for both degradation factors and synthesis factors in the cartilage metabolism. Life Sci. 2016 Aug 1;158:70-7.|[3]da Silva CF, et al. Activities of psilostachyin A and cynaropicrin against Trypanosoma cruzi in vitro and in vivo. Antimicrob Agents Chemother. 2013 Nov;57 (11) :5307-14.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3347), CF740 conjugate, 0.1mg/mL
BNC743347-100 1x 100 µL

NKX3.1 (Metastatic Prostate Adenocarcinoma Marker) (NKX3.1/3347), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
GDC-0941
TRC-G601510-50MG 50 mg

GDC-0941

Sign In for Pricing
View Details
Human p114RhoGEF (ARHGEF18) activation kit by CRISPRa
GA108257 1 Kit

Human p114RhoGEF (ARHGEF18) activation kit by CRISPRa

Sign In for Pricing
View Details
N-(2,3-Dichlorophenyl)piperazine-d8 hydrochloride
TRC-D435752-50MG 50 mg

N-(2,3-Dichlorophenyl)piperazine-d8 hydrochloride

Sign In for Pricing
View Details
SOX9 / SRY-box 9 (PCRP-SOX9-1E5), CF594 conjugate, 0.1mg/mL
BNC941926-100 1x 100 µL

SOX9 / SRY-box 9 (PCRP-SOX9-1E5), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Tissue Protein Lysate, Lymphoid tissue
CP565815 150 µg

Tissue Protein Lysate, Lymphoid tissue

Sign In for Pricing
View Details