Mouse IgG Latex Particles (High Specificity)

<strong>Mouse IgG Latex Particles</strong>_x000D_ <strong>Catalog number:</strong> B2010389_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.5% solid suspension_x000D_ <strong>Supplied as:</strong> Liquid Suspension_x000D_ <strong>Appearance:</strong> White particle suspension_x000D_ <strong>Applications:</strong> high quality suspension of latex particles (~0.35 um) conjugated to a polyclonal mix of mouse IgG. Highly specific and highly stable, these particles can be used for easy one-step capture various antigens, proteins and antibodies specific to mouse IgG. These particles can be recovered easily by centrifugation, allowing for various applications such as purification, depletion, assay development and more._x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> IgG-latex, mouse IgG latex, mouse IgG latex beads_x000D_ <strong>Grade:</strong> Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Dekkers G, Bentlage AEH, Stegmann TC, Howie HL, Lissenberg-Thunnissen S,_x000D_ Zimring J, Rispens T, Vidarsson G. Affinity of human IgG subclasses to mouse Fc_x000D_ gamma receptors. MAbs. 2017 Jul;9(5):767-773._x000D_ _x000D_ 2: Proetzel G, Roopenian DC. Humanized FcRn mouse models for evaluating_x000D_ pharmacokinetics of human IgG antibodies. Methods. 2014 Jan 1;65(1):148-53. d_x000D_ _x000D_ 3: Temming AR, Bentlage AEH, de Taeye SW, Bosman GP, Lissenberg-Thunnissen SN,_x000D_ Derksen NIL, Brasser G, Mok JY, van Esch WJE, Howie HL, Zimring JC, Vidarsson G._x000D_ Cross-reactivity of mouse IgG subclasses to human Fc gamma receptors: Antibody_x000D_ deglycosylation only eliminates IgG2b binding. Mol Immunol. 2020 Nov;127:79-86._x000D_ _x000D_ 4: Choi J, Kim M, Lee J, Seo Y, Ham Y, Lee J, Lee J, Kim JK, Kwon MH. Antigen-_x000D_ binding affinity and thermostability of chimeric mouse-chicken IgY and mouse-_x000D_ human IgG antibodies with identical variable domains. Sci Rep. 2019 Dec_x000D_ 17;9(1):19242._x000D_ _x000D_ 5: Zaytseva OO, Jansen BC, Hanić M, Mrčela M, Razdorov G, Stojković R, Erhardt_x000D_ J, Brizić I, Jonjić S, Pezer M, Lauc G. MIgGGly (mouse IgG glycosylation_x000D_ analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation_x000D_ in mice with nanoUPLC-ESI-MS. Sci Rep. 2018 Sep 12;8(1):13688._x000D_ _x000D_ 6: Nimmerjahn F, Bruhns P, Horiuchi K, Ravetch JV. FcgammaRIV: a novel FcR with_x000D_ distinct IgG subclass specificity. Immunity. 2005 Jul;23(1):41-51._x000D_ _x000D_ 7: Arduin E, Arora S, Bamert PR, Kuiper T, Popp S, Geisse S, Grau R, Calzascia_x000D_ T, Zenke G, Kovarik J. Highly reduced binding to high and low affinity mouse Fc_x000D_ gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse_x000D_ IgG2a. Mol Immunol. 2015 Feb;63(2):456-63._x000D_ _x000D_ 8: Lux A, Nimmerjahn F. Of mice and men: the need for humanized mouse models to_x000D_ study human IgG activity in vivo. J Clin Immunol. 2013 Jan;33 Suppl 1:S4-8._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20015554/">9: Mohanty S, Kim J, Ganesan LP, Phillips GS, Hua K, Jarjoura D, Hayton WL,_x000D_ Robinson JM, Anderson CL. IgG is transported across the mouse yolk sac_x000D_ independently of FcgammaRIIb. J Reprod Immunol. 2010 Mar;84(2):133-44. </a>_x000D_ _x000D_ <strong>Products Related to Mouse IgG Latex Particles </strong> <a href="https://moleculardepot.com/product-category/beads-and-particles/">: Beads and Particles</a>