7030B-C5
7030B-C5 is a PCSK9 inhibitor (IC50=1.61 μM) . 7030B-C5 can significantly reduce plasma cholesterol and triglyceride (TG) levels in vivo and slow the progression of atherosclerosis. 7030B-C5 can be used in the study of cardiovascular diseases[1].
Product Specifications
CAS Number
370871-42-4
UNSPSC
12352005
Target
PCSK9
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/7030b-c5.html
Purity
99.78
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N=C(NCCO)N2CC3=CC=CC(OC)=C3)N(C)C(N1C)=O
Molecular Formula
C17H21N5O4
Molecular Weight
359.38
References & Citations
[1]Xuhui Bao, et al. "Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9) : from bench to bedside." Signal Transduction and Targeted Therapy 9.1 (2024) : 13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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