AWL 60

AWL 60 is a compound with SP antagonist and weak opioid agonist properties, which can antagonize SP-agonists in vitro and attenuate the decrease in blood pressure caused by SP-agonists in vivo.

Product Specifications

CAS Number

[140716-14-9]

UNSPSC

12352209

Target

Neurokinin Receptor; Opioid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/awl-60.html

Smiles

CSCC[C@@H](C(N)=O)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3=CC=CC=C3)NC([C@H](CC4=CC=CC=C4)NC([C@@H](CC5=CC=CC=C5)NC([C@H]6N(C([C@H](CC7=CC=C(O)C=C7)N)=O)CCC6)=O)=O)=O)=O)=O

Molecular Formula

C57H65N9O8S

Molecular Weight

1036.25

References & Citations

[1]Bifunctional pharmacophores. Biological activities of the peptide analog containing both casomorphine-like and substance P antagonist-like active elements