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Dersalazine

Dersalazine (UR-12746 free base) is an inhibitor of platelet-activating factor, exhibiting intestinal anti-inflammatory activity and potential efficacy in treating ulcerative colitis.

Product Specifications

CAS Number

[188913-58-8]

Product Name Alternative

UR-12746 (free base)

UNSPSC

12352005

Target

Platelet-activating Factor Receptor (PAFR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dersalazine.html

Smiles

O=C(O)C1=CC(/N=N/C2=CC=C(/C(C3=CC=CC=C3)=C\C(N4CCC(CN5C(C)=NC6=C5C=CN=C6)CC4)=O)C=C2)=CC=C1O

Molecular Formula

C35H32N6O4

Molecular Weight

600.67

References & Citations

[1]Safety and activity of dersalazine sodium in patients with mild-to-moderate active colitis: double-blind randomized proof of concept study

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

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