Nitenpyram

Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals[1][2].

Product Specifications

CAS Number

[150824-47-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NAChR; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nitenpyram.html

Purity

99.73

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=[N+](/C=C(NC)/N(CC1=CC=C(Cl)N=C1)CC)[O-]

Molecular Formula

C11H15ClN4O2

Molecular Weight

270.72

Precautions

H302, H315, H319, H335

References & Citations

[1]Vo DT, et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J Vet Pharmacol Ther. 2010 Aug;33 (4) :315-22.|[2]Rust MK, et al. Efficacy and longevity of nitenpyram against adult cat fleas (Siphonaptera: Pulicidae) . J Med Entomol. 2003 Sep;40 (5) :678-81.