Dihydroferulic acid

Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid[1][2].

Product Specifications

CAS Number

[1135-23-5]

Product Name Alternative

Hydroferulic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dihydroferulic-acid.html

Purity

99.67

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CCC1=CC=C(O)C(OC)=C1

Molecular Formula

C10H12O4

Molecular Weight

196.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Deters M, et al. Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities. Pharm Res. 2008 Aug;25 (8) :1822-7.|[2]Paola Vitaglionea, et al. Gut fermentation induced by a resistant starch rich whole grain diet explains serum concentration of dihydroferulic acid and hippuric acid in a model of ZDF rats. Journal of Functional Foods. 53 (2019) : 286-291.|[3]Wong CC, et al. Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters. Mol Nutr Food Res. 2011 Jul;55 (7) :979-88.|[4]Beck JJ, et al. Fungicidal activities of dihydroferulic acid alkyl ester analogues. J Nat Prod. 2007 May;70 (5) :779-82.