Dihydroferulic acid
Dihydroferulic acid (Hydroferulic acid) is one of the main metabolites of curcumin and antioxidant/radical-scavenging properties with an IC50 value of 19.5 μM. Dihydroferulic acid is a metabolite of human gut microflora as well as a precursor of vanillic acid[1][2].
Product Specifications
CAS Number
1135-23-5
Product Name Alternative
Hydroferulic acid
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dihydroferulic-acid.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CCC1=CC=C(O)C(OC)=C1
Molecular Formula
C10H12O4
Molecular Weight
196.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Deters M, et al. Different curcuminoids inhibit T-lymphocyte proliferation independently of their radical scavenging activities. Pharm Res. 2008 Aug;25 (8) :1822-7.|[2]Paola Vitaglionea, et al. Gut fermentation induced by a resistant starch rich whole grain diet explains serum concentration of dihydroferulic acid and hippuric acid in a model of ZDF rats. Journal of Functional Foods. 53 (2019) : 286-291.|[3]Wong CC, et al. Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters. Mol Nutr Food Res. 2011 Jul;55 (7) :979-88.|[4]Beck JJ, et al. Fungicidal activities of dihydroferulic acid alkyl ester analogues. J Nat Prod. 2007 May;70 (5) :779-82.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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