Oxaline
Product Specifications
UNSPSC Description
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase[1][2].
Target Antigen
Microtubule/Tubulin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oxaline.html
Solubility
10 mM in DMSO
Smiles
O=C1N[C@@]23N(OC)C4=C(C=CC=C4)[C@]2(C(C)(C)C=C)C=C(OC)C(N3/C1=C/C5=CN=CN5)=O
Molecular Weight
447.49
References & Citations
[1]Nagel D W, et al. X-Ray structure of oxaline: a novel alkaloid from Penicillium oxalicum. Journal of the Chemical Society. Chemical Communications. 1974 (24): 1021-1022.|[2]Koizumi Y, et al. Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization. Biochim Biophys Acta. 2004 Jul 23;1693(1):47-55.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N8287/Oxaline-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N8287/
Clinical Information
No Development Reported
CAS Number
55623-37-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2158252-01 96 Tests
Retinoid X Receptor Alpha (RXRa) Magnetic Fluorescence Assay Kit
Ask
View Details MBS2158252-02 5x 96 Tests
Retinoid X Receptor Alpha (RXRa) Magnetic Fluorescence Assay Kit
Ask
View Details 
MBS2158252-03 10x 96 Tests
Retinoid X Receptor Alpha (RXRa) Magnetic Fluorescence Assay Kit
Ask
View Details 