A-49816
A-49816 is an orally active diuretic that increases urine volume and sodium and chloride excretion. A-49816 at high doses (12.5, 15, and 20 mg) caused significant salt and chloride excretion and diuresis in experimental animals[1].
Product Specifications
CAS Number
[78235-72-0]
UNSPSC
12352005
Target
Vasopressin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/a-49816.html
Smiles
O=C(COC1=CC=C(C(Cl)=C1Cl)C(C2=CC=C(C(CN)=C2)O)=O)OCC
Molecular Formula
C18H17Cl2NO5
Molecular Weight
398.24
References & Citations
[1]Luther RR, et al. Pharmacologic effects of A-49816, a new high-ceiling diuretic. J Clin Pharmacol. 1987 Oct;27 (10) :794-801.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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