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A-49816

A-49816 is an orally active diuretic that increases urine volume and sodium and chloride excretion. A-49816 at high doses (12.5, 15, and 20 mg) caused significant salt and chloride excretion and diuresis in experimental animals[1].

Product Specifications

CAS Number

78235-72-0

UNSPSC

12352005

Target

Vasopressin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/a-49816.html

Smiles

O=C(COC1=CC=C(C(Cl)=C1Cl)C(C2=CC=C(C(CN)=C2)O)=O)OCC

Molecular Formula

C18H17Cl2NO5

Molecular Weight

398.24

References & Citations

[1]Luther RR, et al. Pharmacologic effects of A-49816, a new high-ceiling diuretic. J Clin Pharmacol. 1987 Oct;27 (10) :794-801.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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