PDE3B-IN-1

PDE3B-IN-1 is a selective inhibitor for phosphodiesterase PDE3B with an IMAP pIC50 of 6.5 and a PDE3B/A selective index >300[1].

Product Specifications

CAS Number

[3032458-01-5]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pde3b-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(NC(C2=NC3=CC(OC)=CC=C3C(OC)=C2)=O)=CC(B(O)O)=C1)NC(C)COC

Molecular Formula

C23H26BN3O7

Molecular Weight

467.28

References & Citations

[1]Rowley AM, et al., Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library. J Med Chem. 2024 Feb 8;67 (3) :2049-2065.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE3

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-12051PE 0.1 mL

Mouse Monoclonal Fc epsilon RI Antibody (IE7) [PE]

Ask

View Details

MBS7048889-01 0.05 mg

PLA2G10 Antibody, FITC conjugated

Ask

View Details

MBS7048889-02 0.1 mg

PLA2G10 Antibody, FITC conjugated

Ask

View Details

MBS7048889-03 5x 0.1 mg

PLA2G10 Antibody, FITC conjugated

Ask

View Details

C6383 96 Tests

Cutaneous T-Cell Lymphocyte Associated Antigen (CTAGE) Chicken ELISA Kit

Ask

View Details

441783-01 10 g

Arsenic Oxide (As2O3) discontinued. See 235340

Ask

View Details