PDE3B-IN-1
PDE3B-IN-1 is a selective inhibitor for phosphodiesterase PDE3B with an IMAP pIC50 of 6.5 and a PDE3B/A selective index >300[1].
Product Specifications
CAS Number
[3032458-01-5]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pde3b-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(NC(C2=NC3=CC(OC)=CC=C3C(OC)=C2)=O)=CC(B(O)O)=C1)NC(C)COC
Molecular Formula
C23H26BN3O7
Molecular Weight
467.28
References & Citations
[1]Rowley AM, et al., Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library. J Med Chem. 2024 Feb 8;67 (3) :2049-2065.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE3
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
QP7349-ec-1mg 1mg
Recombinant S. aureus Replication initiation protein Protein, His-SUMO, E.coli-1mg
Ask
View Details 
