PDE3B-IN-1
PDE3B-IN-1 is a selective inhibitor for phosphodiesterase PDE3B with an IMAP pIC50 of 6.5 and a PDE3B/A selective index >300[1].
Product Specifications
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pde3b-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(NC(C2=NC3=CC(OC)=CC=C3C(OC)=C2)=O)=CC(B(O)O)=C1)NC(C)COC
Molecular Formula
C23H26BN3O7
Molecular Weight
467.28
References & Citations
[1]Rowley AM, et al., Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library. J Med Chem. 2024 Feb 8;67 (3) :2049-2065.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163285/PDE3B-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163285/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE3
CAS Number
[3032458-01-5]
Available Sizes
Curated Selection
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