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Anti-Mouse OX40L/CD134L Antibody (RM134L)

Anti-Mouse OX40L/CD134L Antibody (RM134L) is an anti-mouse OX40L/CD134L IgG2b monoclonal antibody. Anti-Mouse OX40L/CD134L Antibody (RM134L) reduces immune response by inhibiting the OX40/OX40L signaling pathway. Anti-Mouse OX40L/CD134L Antibody (RM134L) can inhibit plasma cell differentiation and antibody secretion. Anti-Mouse OX40L/CD134L Antibody (RM134L) can prolong the survival time of cell transplantation by inhibiting CD4+ T cells. Anti-Mouse OX40L/CD134L Antibody (RM134L) can be used for researches on inflammation and cancer such as graft versus host disease (GVHD), allergic reaction, lupus nephritis and hepatocellular carcinoma (HCC) [1][2][3][4].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Orexin Receptor (OX Receptor)

Type

Inhibitory Antibodies

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-ox40l-cd134l-antibody-rm134l.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseOX40L/CD134LAntibody(RM134L)]

Molecular Weight

(150 kDa)

References & Citations

[1]Gattringer M, et al. Anti-OX40L alone or in combination with anti-CD40L and CTLA4Ig does not inhibit the humoral and cellular response to a major grass pollen allergen. Clin Exp Allergy. 2016 Feb;46 (2) :354-64.|[2]Blazar BR, et al. Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients. Blood. 2003 May 1;101 (9) :3741-8.|[3]Zhang F, et al. Activation of NOD1 on tumor-associated macrophages augments CD8+ T cell-mediated antitumor immunity in hepatocellular carcinoma. Sci Adv. 2024 Oct 4;10 (40) :eadp8266. |[4]Zhao J, et al. Blockade of OX40/OX40L signaling using anti-OX40L alleviates murine lupus nephritis. Eur J Immunol. 2024 Aug;54 (8) :e2350915.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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