2-Aminopurine
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics[1][2].
Product Specifications
CAS Number
452-06-2
UNSPSC
12171500
Hazard Statement
H302
Target
DNA Stain
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-aminopurine.html
Purity
99.61
Solubility
DMSO : 5 mg/mL (ultrasonic) |H2O : 1.35 mg/mL (ultrasonic)
Smiles
NC1=NC=C2NC=NC2=N1
Molecular Formula
C5H5N5
Molecular Weight
135.13
Precautions
H302
References & Citations
[1]J M Jean, et al. 2-Aminopurine fluorescence quenching and lifetimes: role of base stacking. Proc Natl Acad Sci U S A. 2001 Jan 2;98 (1) :37-41.|[2]Dehong Tan, et al. Decreased glycation and structural protection properties of γ-glutamyl-S-allyl-cysteine peptide isolated from fresh garlic scales (Allium sativum L.) . Nat Prod Res. 2015;29 (23) :2219-22.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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