Estrogen Receptor (AER314), 0.2mg/mL

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ESR1

Gene ID

2099

NCBI Gene ID

208124

UniProt

P03372

Swiss Prot

P03372

Host

Mouse

Species Reactivity

Cow,Human,Mouse,Rabbit,Rat

Reactivity

Estrogen Receptor

Immunogen

ER purified from cow uterus

Target Antigen

Estrogen Receptor

Clonality

Monoclonal

Clone

AER314

Type

Primary

Source

Animal

Origin

Animal

Field of Research

Cancer, Endocrinology, Nuclear receptors

Positive Control

MCF-7 Cells or Breast Cancers.

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

67 kDa

References & Citations

Abbondanza C et. al. Steroids, 1993, 58:4-12

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA

Documents

Product Datasheet

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