Estrogen Receptor (AER314), 0.2mg/mL
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
CAS Number
9007-83-4
Synonyms
Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ESR1
Gene ID
2099
NCBI Gene ID
208124
UniProt
P03372
Swiss Prot
P03372
Host
Mouse
Species Reactivity
Cow,Human,Mouse,Rabbit,Rat
Reactivity
Estrogen Receptor
Immunogen
ER purified from cow uterus
Target Antigen
Estrogen Receptor
Clonality
Monoclonal
Clone
AER314
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cancer, Endocrinology, Nuclear receptors
Positive Control
MCF-7 Cells or Breast Cancers.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
67 kDa
References & Citations
Abbondanza C et. al. Steroids, 1993, 58:4-12
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA
Documents
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