CP-690550A

CP-690550A is an analogue of Tofacitinib (HY-40354) . CP-690550A is a dual inhibitor of JAK2 and JAK3[1].

Product Specifications

CAS Number

[1243290-37-0]

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cp-690550a.html

Smiles

CN([C@H]1CN(CC[C@H]1C)C(CO)=O)C2=C3C(NC=C3)=NC=N2

Molecular Formula

C15H21N5O2

Molecular Weight

303.36

References & Citations

[1]Chrencik JE, et al. Structural and thermodynamic characterization of the TYK2 and JAK3 kinase domains in complex with CP-690550 and CMP-6. J Mol Biol. 2010 Jul 16;400 (3) :413-33.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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