Recombinant Human CDK2 & Cyclin E1 Protein (Full Length, GST Tag, Active)

<strong>Recombinant Human CDK2 &amp; Cyclin E1 Protein (Full Length, GST Tag, Active)</strong>_x000D_ <strong>Catalog number:</strong> B2019028_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> CDK2 ~58 kDa; CyclinE1 ~73kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> Recombinant Human CDK2 &amp; Cyclin E1 Protein (Full Length, GST Tag), Active_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Li Y, Yang XH, Fang SJ, Qin CF, Sun RL, Liu ZY, Jiang BY, Wu X, Li G. HOXA7 stimulates human hepatocellular carcinoma proliferation through cyclin E1/CDK2 Oncol Rep. 2015 Feb;33(2):990-6._x000D_ 2: Honda R, Lowe ED, Dubinina E, Skamnaki V, Cook A, Brown NR, Johnson LN. The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles EMBO J. 2005 Feb 9;24(3):452-63._x000D_ 3: Sandhu C, Donovan J, Bhattacharya N, Stampfer M, Worland P, Slingerland J. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells Oncogene. 2000 Nov 9;19(47):5314-23._x000D_ 4: Lin BY, Ma T, Liu JS, Kuo SR, Jin G, Broker TR, Harper JW, Chow LT. HeLa cells are phenotypically limiting in cyclin E/CDK2 for efficient human papillomavirus DNA replication J Biol Chem. 2000 Mar 3;275(9):6167-74._x000D_ 5: Gurzov EN, Izquierdo M. Cyclin E1 knockdown induces apoptosis in cancer cells Neurol Res. 2006 Jul;28(5):493-9._x000D_ 6: Johansson C, Graham SV, Dornan ES, Morgan IM. The human papillomavirus 16 E2 protein is stabilised in S phase Virology. 2009 Nov 25;394(2):194-9._x000D_ 7: Lee MC, Hsieh CH, Wei SC, Shen SC, Chen CN, Wu VC, Chuang LY, Hsieh FJ, Wu CH, Tsai-Wu JJ. Ectopic EBP2 expression enhances cyclin E1 expression and induces chromosome instability in HEK293 stable clones BMB Rep. 2008 Oct 31;41(10):716-21._x000D_ 8: Boratyn E, Nowak I, Karnas E, Ryszawy D, Wnuk D, Polus A, Durbas M, Horwacik I, Rokita H. MCPIP1 overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block J Cell Biochem. 2020 Jun;121(5-6):3406-3425._x000D_ 9: Kfir-Erenfeld S, Haggiag N, Biton M, Stepensky P, Assayag-Asherie N, Yefenof E. miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis Oncotarget. 2017 Jan 3;8(1):472-489._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15665273">10: Hayami R, Sato K, Wu W, Nishikawa T, Hiroi J, Ohtani-Kaneko R, Fukuda M, Ohta T. Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2 Cancer Res. 2005 Jan 1;65(1):6-10.</a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human CDK2 &amp; Cyclin E1 Protein (Full Length, GST Tag, Active) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>