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Avarone

Avarone ((+) -Avarone) is a sesquiterpenoidal quinone that can be isolated from Dysidea avara. Avarone shows cytotoxicity. Avarone shows antileukemic activity[1][2].

Product Specifications

CAS Number

55303-99-6

Product Name Alternative

(+) -Avarone

UNSPSC

12352211

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/avarone.html

Smiles

O=C1C(C[C@]2(C)[C@@H](C)CC[C@]3(C)C(C)=CCC[C@@]23[H])=CC(C=C1)=O

Molecular Formula

C21H28O2

Molecular Weight

312.45

References & Citations

[1]Sakurai J, et al. Highly efficient total synthesis of the marine natural products (+) -avarone, (+) -avarol, (-) -neoavarone, (-) -neoavarol and (+) -aureol. Chemistry. 2008;14 (3) :829-37.|[2]Müller WE, et al. Potent antileukemic activity of the novel cytostatic agent avarone and its analogues in vitro and in vivo. Cancer Res. 1985 Oct;45 (10) :4822-6.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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