GSK8062
GSK8062 is a farnesoid X receptor (FXR) agonist with activity that improves compound development parameters. Analog 1c of GSK8062 showed a reduction in weight gain and serum glucose levels[1].
Product Specifications
CAS Number
[943549-47-1]
UNSPSC
12352005
Target
FXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gsk8062.html
Smiles
O=C(C1=C2C=CC(C3=CC=C(OCC4=C(C(C)C)ON=C4C5=C(Cl)C=CC=C5Cl)C=C3)=CC2=CC=C1)O
Molecular Formula
C30H23Cl2NO4
Molecular Weight
532.41
References & Citations
[1]Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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