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[D-Leu-4]-OB3

Product Specifications

UNSPSC Description

[D-Leu-4]-OB3 inhibits expressions of pro-inflammatory, proliferative and metastatic genes and PD-L1 expression. [D-Leu-4]-OB3 stimulates expression of pro-apoptotic genes[1].

Target Antigen

Apoptosis; PD-1/PD-L1

Type

Peptides

Related Pathways

Apoptosis;Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/d-leu-4-ob3.html

Purity

99.31

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CCC(N)=O)NC([C@H]1N(CCC1)C([C@@H](CC(C)C)NC([C@H](CO)NC([C@H](CS)NC([C@@H](N)CO)=O)=O)=O)=O)=O)=O

Molecular Weight

734.82

References & Citations

[1]Yih Ho,et al. Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells.Food Chem Toxicol. 2019 Nov;133:110808.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P3342/D-Leu-4-OB3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P3342/D-Leu-4-OB3-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

289056-32-2

Available Sizes

Curated Selection

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