[D-Leu-4]-OB3
Product Specifications
UNSPSC Description
[D-Leu-4]-OB3 inhibits expressions of pro-inflammatory, proliferative and metastatic genes and PD-L1 expression. [D-Leu-4]-OB3 stimulates expression of pro-apoptotic genes[1].
Target Antigen
Apoptosis; PD-1/PD-L1
Type
Peptides
Related Pathways
Apoptosis;Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/d-leu-4-ob3.html
Purity
99.31
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CCC(N)=O)NC([C@H]1N(CCC1)C([C@@H](CC(C)C)NC([C@H](CO)NC([C@H](CS)NC([C@@H](N)CO)=O)=O)=O)=O)=O)=O
Molecular Weight
734.82
References & Citations
[1]Yih Ho,et al. Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells.Food Chem Toxicol. 2019 Nov;133:110808.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3342/D-Leu-4-OB3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3342/D-Leu-4-OB3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
289056-32-2
Available Sizes
Curated Selection
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