5-Methoxy-DL-tryptophan

5-Methoxy-DL-tryptophan is a metabolite. 5-Methoxy-DL-tryptophan reduces LPS (HY-D1056) -induced release of IL-6. 5-Methoxy-DL-tryptophan has anti-inflammatory effects. 5-Methoxy-DL-tryptophan can be used in the study of atherosclerosis[1][2].

Product Specifications

CAS Number

[28052-84-8]

Product Name Alternative

DL-5-MTP

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Interleukin Related

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/5-methoxy-dl-tryptophan.html

Purity

99.32

Solubility

1M HCl : 100 mg/mL (ultrasonic) |DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC(CC1=CNC2=C1C=C(OC)C=C2)C(O)=O

Molecular Formula

C12H14N2O3

Molecular Weight

234.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Lee GL, et al. Restoration of 5-methoxytryptophan protects against atherosclerotic chondrogenesis and calcification in ApoE-/- mice fed high fat diet. J Biomed Sci. 2021 Nov 8;28 (1) :74. |[2]Menzaghi C, et al. Inflammation and prediction of death in type 2 diabetes. Evidence of an intertwined link with tryptophan metabolism. J Clin Endocrinol Metab. 2024 Aug 28:dgae593.