Phytol

Phytol ((E) -Phytol) is an orally active diterpenoid alcohol that can be extracted from chlorophyll. Phytol has antioxidant, anti-inflammatory, anti-schistosomiasis and antibacterial activities[1][2][3].

Product Specifications

CAS Number

[150-86-7]

Product Name Alternative

(E) -Phytol

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Keap1-Nrf2; Parasite

Type

Natural Products

Related Pathways

Anti-infection; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/phytol.html

Purity

99.76

Solubility

DMSO : 125 mg/mL (ultrasonic) |Ethanol : 25 mg/mL (ultrasonic)

Smiles

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(C)=C/CO

Molecular Formula

C20H40O

Molecular Weight

296.53

Precautions

H302, H315, H319, H335

References & Citations

[1]de Moraes J, et al. Phytol, a diterpene alcohol from chlorophyll, as a drug against neglected tropical diseaseSchistosomiasis mansoni. PLoS Negl Trop Dis. 2014 Jan 2;8 (1) :e2617.|[2]Kim EN, et al. Phytol Suppresses Osteoclast Differentiation and Oxidative Stress through Nrf2/HO-1 Regulation in RANKL-Induced RAW264.7 Cells. Cells. 2022 Nov 14;11 (22) :3596.|[3]Usman MA, et al. Phytol suppresses parasitemia and ameliorates anaemia and oxidative brain damage in mice infected with Plasmodium berghei. Exp Parasitol. 2021 May;224:108097.