Satraplatin

Satraplatin is an alkylating agent, with potent antitumor effect.

Product Specifications

CAS Number

[129580-63-8]

Product Name Alternative

BMS182751; BMY45594; JM216

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

DNA Alkylator/Crosslinker

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Satraplatin.html

Purity

99.79

Solubility

DMF : 10 mg/mL (ultrasonic; adjust pH to 1 with HCl) |DMSO : 35.71 mg/mL (ultrasonic)

Smiles

[Cl-][Pt+4]([O-]C(C)=O)([O-]C(C)=O)([Cl-])([NH3])[NH2]C1CCCCC1

Molecular Formula

C10H22Cl2N2O4Pt

Molecular Weight

500.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Fiebiger W, et al. In vitro cytotoxicity of novel platinum-based drugs and dichloroacetate against lung carcinoid cell lines. Clin Transl Oncol. 2011 Jan;13 (1) :43-9.|[2]Yamano Y, et al. Antitumor activity of satraplatin in cisplatin-resistant oral squamous cell carcinoma cells. Head Neck. 2011 Mar;33 (3) :309-17.