Satraplatin
Satraplatin is an alkylating agent, with potent antitumor effect.
Product Specifications
CAS Number
129580-63-8
Product Name Alternative
BMS182751; BMY45594; JM216
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Satraplatin.html
Purity
99.79
Solubility
DMF : 10 mg/mL (ultrasonic; adjust pH to 1 with HCl) |DMSO : 35.71 mg/mL (ultrasonic)
Smiles
[Cl-][Pt+4]([O-]C(C)=O)([O-]C(C)=O)([Cl-])([NH3])[NH2]C1CCCCC1
Molecular Formula
C10H22Cl2N2O4Pt
Molecular Weight
500.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Fiebiger W, et al. In vitro cytotoxicity of novel platinum-based drugs and dichloroacetate against lung carcinoid cell lines. Clin Transl Oncol. 2011 Jan;13 (1) :43-9.|[2]Yamano Y, et al. Antitumor activity of satraplatin in cisplatin-resistant oral squamous cell carcinoma cells. Head Neck. 2011 Mar;33 (3) :309-17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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