CYP51-IN-13

CYP51-IN-2 (compound 1m), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80s of 62.5 and 250 ng/mL for Microsporum gypseum and Candida albicans, respectively[1].

Product Specifications

CAS Number

[1155361-11-7]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyp51-in-13.html

Smiles

OC(CN(CC1=CC=C(CC)C=C1)CC=C)(C2=CC=C(F)C=C2F)CN3N=CN=C3

Molecular Formula

C23H26F2N4O

Molecular Weight

412.48

References & Citations

[1]Chai X, et, al. Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase. Eur J Med Chem. 2009 May;44 (5) :1913-20.