BN-82451 (dihydrochloride)
BN-82451 dihydrochloride, an orally active and CNS-penetrated antioxidant and a multitargeting neuroprotective agent, exert a significant protection in experimental animal models mimicking aspects of cerebral ischemia, Parkinson disease, Huntington disease, and more particularly amyotrophic lateral sclerosis[1][2].
Product Specifications
CAS Number
663172-95-0
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bn-82451-dihydrochloride.html
Smiles
OC1=C(C(C)(C)C)C=C(C2=CSC(CN)=N2)C=C1C(C)(C)C.Cl.Cl
Molecular Formula
C18H28Cl2N2OS
Molecular Weight
391.40
References & Citations
[1]Anthony J Hannan, et al. Novel therapeutic targets for Huntington's disease. Expert Opin Ther Targets. 2005 Aug;9 (4) :639-50.|[2]Pierre Etienne Chabrier, et al. Pharmacological properties of BN82451: a novel multitargeting neuroprotective agent. CNS Drug Rev. 2007 Fall;13 (3) :317-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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