YM-16638
YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC4, LTD4, and LTE4 in guinea pig trachea, with IC50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep[1].
Product Specifications
CAS Number
[104073-72-5]
Product Name Alternative
YM 638
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ym-16638.html
Smiles
O=C(O)CSC1=NN=C(SCCCOC2=CC=C(C(C)=O)C(O)=C2CCC)S1
Molecular Formula
C18H22N2O5S3
Molecular Weight
442.57
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19042/YM-16638-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19042/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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