(1R,2S) -VU0155041
(1R,2S) -VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM.
Product Specifications
CAS Number
[1263273-14-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_1R,2S_-VU0155041.html
Purity
95.09
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@H]1[C@@H](C(NC2=CC(Cl)=CC(Cl)=C2)=O)CCCC1)O
Molecular Formula
C14H15Cl2NO3
Molecular Weight
316.18
Precautions
H315, H319, H335
References & Citations
[1]Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positiveallosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74 (5) :1345-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR4
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV726401 1.0 µg DNA
FXYD6P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
MBS6354387-01 0.1 mL
TCEAL6, NT (TCEAL6, Transcription elongation factor A protein-like 6, Transcription elongation factor S-II protein-like 6) (MaxLight 490)
Sign In for Pricing
View Details 
MBS6354387-02 5x 0.1 mL
TCEAL6, NT (TCEAL6, Transcription elongation factor A protein-like 6, Transcription elongation factor S-II protein-like 6) (MaxLight 490)
Sign In for Pricing
View Details NBP3-08375AF405 100 µL
Mouse Monoclonal Napsin A Antibody (NAPSA/3305) [Alexa Fluor 405]
Sign In for Pricing
View Details bs-9939R-PerCP 100 µL
C11orf57 Polyclonal Antibody, PerCP Conjugated
Sign In for Pricing
View Details 
GTR15190607 1 Vial
Lentiviral mouse P2ry6 shRNA (UAS) - Lentiviral mouse P2ry6 shRNA (UAS, RFP) (25)
Sign In for Pricing
View Details