(1R,2S) -VU0155041
(1R,2S) -VU0155041, Cis regioisomer of VU0155041, is a partial mGluR4 agonist with an EC50 of 2.35 μM.
Product Specifications
CAS Number
[1263273-14-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_1R,2S_-VU0155041.html
Purity
95.09
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@H]1[C@@H](C(NC2=CC(Cl)=CC(Cl)=C2)=O)CCCC1)O
Molecular Formula
C14H15Cl2NO3
Molecular Weight
316.18
Precautions
H315, H319, H335
References & Citations
[1]Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positiveallosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74 (5) :1345-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR4
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K7086104 1.0 µg DNA
Slc26a2 sgRNA CRISPR Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details PLAC9-3277R 50 µg
Recombinant Rhesus Macaque PLAC9 Protein, His (Fc)-Avi-tagged
Sign In for Pricing
View Details K0339502 1.0 µg DNA
C21orf32 sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details 244846 50 µL
COMMD1 (Copper Metabolism (Murr1) Domain Containing 1, C2orf5, MGC27155, MURR1)
Sign In for Pricing
View Details 
