TC13172
Product Specifications
UNSPSC Description
TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2 nM for HT-29 cells[1].
Target Antigen
Mixed Lineage Kinase
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/TC13172.html
Purity
99.04
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N=C(S(C)(=O)=O)N2C)N(CC#CC3=CC(O)=CC=C3)C(N1C)=O
Molecular Weight
388.40
References & Citations
[1]Bo Yan, et al. Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein.ChemCommun (Camb). 2017 Mar 28;53(26):3637-3640.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101524/TC13172-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101524/TC13172-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2093393-05-4
Available Sizes
Curated Selection
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