PDE4B/D-IN-4
PDE4B/D-IN-4 (compound 4p) is a potent inhibitor of PDE-4B and PDE-4D, with IC50s of 5.50 nM and 6.81 nM, respectively. PDE4B/D-IN-4 shows an increase in the level of intracellular cAMP[1].
Product Specifications
UNSPSC
12352211
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pde4b-d-in-4.html
Smiles
O=C(N/N=C/C1=CC=C(OC)C(O)=C1)C2=CC=C(OC(F)F)C(OCC3CC3)=C2
Molecular Formula
C20H20F2N2O5
Molecular Weight
406.38
References & Citations
[1]Ahmed M Moussa, et al. Rationale design and synthesis of new roflumilast analogues as preferential selective and potent PDE-4B inhibitors. Bioorg Chem. 2024 Oct 24:153:107911
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Monoclonal TrkC Antibody (1) [DyLight 550]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP2-89240R 0.1 mL
Rabbit Monoclonal TrkC Antibody (1) [DyLight 550]
Sign In for Pricing
View Details E-HD-C091 20 Tests
Human Vibrio cholerae O1/O139 Antigen Combo Lateral Flow Assay Kit
Sign In for Pricing
View Details 
K4645506 1.0 µg DNA
Ap2b1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details