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Pipemidic acid

Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections[1][2].

Product Specifications

CAS Number

51940-44-4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Pipemidic-acid.html

Purity

98.0

Solubility

1M NaOH : 100 mg/mL (ultrasonic; adjust pH to 12 with NaOH) |DMSO : 5 mg/mL (ultrasonic)

Smiles

O=C(C1=CN(CC)C2=NC(N3CCNCC3)=NC=C2C1=O)O

Molecular Formula

C14H17N5O3

Molecular Weight

303.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Iacovino R, et al. β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. Int J Mol Sci. 2013 Jun 25;14 (7) :13022-41.|[2]Aoyama H, et, al. Purification of Citrobacter freundii DNA gyrase and inhibition by quinolones. Antimicrob Agents Chemother. 1988 Jan;32 (1) :104-9. |[3]Shimizu M, et, al. Pipemidic acid: absorption, distribution, and excretion. Antimicrob Agents Chemother. 1975 Apr;7 (4) :441-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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