BMI-1 Antibody Monoclonal

<strong>BMI-1 Antibody Monoclonal</strong>_x000D_ <strong>Catalog number:</strong> B2016820_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µL_x000D_ <strong>Molecular Weight or Concentration:</strong> 40 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> PCGF4, RNF51, FLVI2/BMI1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Polmear J, Hailes L, Olshansky M, Rischmueller M, L'Estrange-Stranieri E, Fletcher AL, Hibbs ML, Bryant VL, Good-Jacobson KL. Targeting BMI-1 to deplete antibody-secreting cells in autoimmunity Clin Transl Immunology. 2023 Oct 4;12(10):e1470._x000D_ 2: Di Pietro A, Polmear J, Cooper L, Damelang T, Hussain T, Hailes L, O'Donnell K, Udupa V, Mi T, Preston S, Shtewe A, Hershberg U, Turner SJ, La Gruta NL, Chung AW, Tarlinton DM, Scharer CD, Good-Jacobson KL. Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection Nat Immunol. 2022 Jan;23(1):86-98._x000D_ 3: Zhang J, Fan J, Zeng X, Nie M, Luan J, Wang Y, Ju D, Yin K. Hedgehog signaling in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment Acta Pharm Sin B. 2021 Mar;11(3):609-620._x000D_ 4: Liu J, Luo B, Zhao M. Bmi‚Äë1‚Äëtargeting suppresses osteosarcoma aggressiveness through the NF‚ÄëŒ∫B signaling pathway Mol Med Rep. 2017 Dec;16(6):7949-7958._x000D_ 5: Herzog AE, Warner KA, Zhang Z, Bellile E, Bhagat MA, Castilho RM, Wolf GT, Polverini PJ, Pearson AT, N√∂r JE. The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells Cell Death Dis. 2021 Oct 23;12(11):988._x000D_ 6: Bolomsky A, Schlangen K, Schreiner W, Zojer N, Ludwig H. Targeting of BMI-1 with PTC-209 shows potent anti-myeloma activity and impairs the tumour microenvironment J Hematol Oncol. 2016 Mar 2;9:17._x000D_ 7: Tong YQ, Liu B, Zheng HY, He YJ, Gu J, Li F, Li Y. BMI-1 autoantibody as a new potential biomarker for cervical carcinoma PLoS One. 2011;6(11):e27804._x000D_ 8: Liu JH, Song LB, Zhang X, Guo BH, Feng Y, Li XX, Liao WT, Zeng MS, Huang KH. Bmi-1 expression predicts prognosis for patients with gastric carcinoma J Surg Oncol. 2008 Mar 1;97(3):267-72._x000D_ 9: Ma DQ, Zhang YH, Ding DP, Li J, Chen LL, Tian YY, Ao KJ. Effect of Bmi-1-mediated NF-Œ∫B signaling pathway on the stem-like properties of CD133+ human liver cancer cells Cancer Biomark. 2018;22(3):575-585._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20630502">10: Kim RH, Lieberman MB, Lee R, Shin KH, Mehrazarin S, Oh JE, Park NH, Kang MK. Bmi-1 extends the life span of normal human oral keratinocytes by inhibiting the TGF-beta signaling Exp Cell Res. 2010 Oct 1;316(16):2600-8. </a>_x000D_ _x000D_ <strong>Products Related to BMI-1 Antibody Monoclonal can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>