HGPR91 antagonist 1
HGPR91 antagonist 1 (Compound 4c) is a potent and selective GPR91 antagonist with an IC50 of 7 nM for human GPR91[1].
Product Specifications
CAS Number
[1314796-00-3]
UNSPSC
12352005
Target
Succinate Receptor 1
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hgpr91-antagonist-1.html
Purity
99.94
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(N[C@@H](C)C1=CC=C(C2=CC=C(F)C(C(F)(F)F)=C2)C=C1)CC3=CC=C(C4=NC5=NC=CC=C5C=C4)C=C3
Molecular Formula
C31H23F4N3O
Molecular Weight
529.53
References & Citations
[1]Bhuniya D, et al. Discovery of a potent and selective small molecule hGPR91 antagonist. Bioorg Med Chem Lett. 2011 Jun 15;21 (12) :3596-602.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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