RR6
RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively[1].
Product Specifications
CAS Number
1351758-37-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Pantetheinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/RR6.html
Purity
99.65
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(C)(CO)[C@@H](O)C(NCCC(CC1=CC=CC=C1)=O)=O
Molecular Formula
C16H23NO4
Molecular Weight
293.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Jansen PA et al. Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol. 2013 Mar 15;8 (3) :530-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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