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RR6

RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively[1].

Product Specifications

CAS Number

1351758-37-6

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Pantetheinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/RR6.html

Purity

99.65

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CC(C)(CO)[C@@H](O)C(NCCC(CC1=CC=CC=C1)=O)=O

Molecular Formula

C16H23NO4

Molecular Weight

293.36

Precautions

H302, H315, H319, H335

References & Citations

[1]Jansen PA et al. Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol. 2013 Mar 15;8 (3) :530-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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