Lactoferrin (17-41) (acetate)

Lactoferrin 17-41 (Lactoferricin B) acetate, a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 acetate has antitumor activities[1][2].

Product Specifications

CAS Number

[2828433-30-1]

Product Name Alternative

Lactoferricin B (acetate) ; Lfcin B (acetate)

UNSPSC

12352209

Target

Apoptosis; Bacterial; Fungal

Type

Peptides

Related Pathways

Anti-infection; Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/lactoferrin-17-41-acetate.html

Purity

99.39

Solubility

H2O : 25.7 mg/mL (ultrasonic; warming) |DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N[C@@H](CCC(N)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](C)C(N4[C@]([H])(C(N[C@@H](CO)C(N[C@@]([H])([C@H](CC)C)C(N[C@@]([H])([C@@H](C)O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(O)=O)=O)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(C)C)=O)CSSC[C@H](NC([C@@H](NC([C@H](CC6=CC=CC=C6)N)=O)CCCCN)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H]1CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O)=O)=O)CCC4)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C)=O

Molecular Formula

C143H226N46O33S3

Molecular Weight

3183.82

References & Citations

[1]Samuelsen Ø, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41 (2) :141-8.|[2]Jiang R, et al. Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells (HT-29) by activating various signaling pathways. Biochem Cell Biol. 2017 Feb;95 (1) :99-109.|[3]Latorre D, et al. Reciprocal interactions between lactoferrin and bacterial endotoxins and their role in the regulation of the immune response. Toxins (Basel) . 2010;2 (1) :54‐68.