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CDw75 (LN-1), 0.2mg/mL

Recognizes a neuraminidase-sensitive sialoprotein (CDw75), present on cell membrane and cytoplasm of germinal center B-cells and derived lymphomas. This MAb reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin's disease. It is shown to be a helpful antibody for ascribing a B-cell phenotype in known lymphoid tissues. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Specifications

CAS Number

9007-83-4

Synonyms

6-sialyltransferase 1 (6-ST1) | Alpha 2,6 ST1 | Beta galactoside alpha 2,6 sialyltransferase 1 | CMP N acetylneuraminate beta galactosamide alpha 2,6 sialyltransferase 1 | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2 | SIAT1 | ST6 beta galactosamide alpha 2,6 sialyltranferase 1 | ST6Gal I | ST6N

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ST6GAL1

Gene ID

6480

NCBI Gene ID

207459

UniProt

P15907

Swiss Prot

P15907

Host

Mouse

Species Reactivity

Human

Reactivity

CDw75

Immunogen

Nuclei from pokeweed mitogen-stimulated peripheral blood lymphocytes.

Target Antigen

CDw75

Clonality

Monoclonal

Clone

LN-1

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (verified) |IF (verified) |IHC, FFPE (verified)

Field of Research

Immunology

Positive Control

HeLa or Daudi Cells. Germinal center B-cells in a lymph node or tonsil. Use LN1 s ability to stain surface of erythrocytes as an internal positive control.

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

46 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgM, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA

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