Aerophobin-2
Aerophobin-2 is a bromine compound, which can be isolated from sponge Verongia aerophoba. Aerophobin-2 inhibits aggregation of α-synuclein (α-syn) and phosphorylated α-synuclein (pSyn), exhibits neuroprotective efficacy[1].
Product Specifications
CAS Number
87075-23-8
UNSPSC
12352005
Target
α-synuclein
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aerophobin-2.html
Smiles
O[C@@H]1[C@@]2(C=C(C(OC)=C1Br)Br)CC(C(NCCCC3=CN=C(N3)N)=O)=NO2
Molecular Formula
C16H19Br2N5O4
Molecular Weight
505.16
References & Citations
[1]Prebble D W, et al. α-synuclein aggregation inhibitory activity of the bromotyrosine derivatives aerothionin and aerophobin-2 from the subtropical marine sponge Aplysinella sp[J]. Results in chemistry, 2022, 4: 100472.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation
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