PF-06869206
PF-06869206 is an orally bioavailable selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with an IC50 of 380 nM[1].
Product Specifications
CAS Number
2227425-05-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/PF-06869206.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=C(C)NC2=C(N3C[C@@H](CO)OCC3)C(C#N)=C(C(F)(F)F)N=C21
Molecular Formula
C15H14ClF3N4O2
Molecular Weight
374.75
Precautions
H302, H315, H319, H335
References & Citations
[1]Filipski KJ, et al. Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1) . ACS Med Chem Lett. 2018 Apr 12;9 (5) :440-445.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RG237006 10 µg
Chimaerin 2 (CHN2) (NM_001293081) Human Tagged ORF Clone
Sign In for Pricing
View Details 
