CD98 (IPO-T10), 0.2mg/mL

CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Specifications

CAS Number

9007-83-4

Synonyms

4F2, 4F2HC, 4T2HC, CD98HC; MDU1; NACAE; Slc3a2; Solute Carrier Family 3 (activators of dibasic and neutral amino acid transport) Member 2, E16, LAT1, MPE16, hLAT1

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

SLC3A2

Gene ID

6520

NCBI Gene ID

502769

UniProt

P08195

Swiss Prot

P08195

Host

Mouse

Species Reactivity

Human

Reactivity

CD98

Immunogen

Molt 13 T cell line

Target Antigen

CD98

Clonality

Monoclonal

Clone

IPO-T10

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published) |IF (expected)

Field of Research

Transporters

Positive Control

HL-60, Jurkat, MG63, HUT-78, K562, YT, U937, Hep-G2 cells, Tonsil

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

Heterodimer (125 kDa) made of a disulfide-linked glycosylated heavy chain of approximately 80-90 kDa and a non-glycosylated light chain

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Int Immunol (2000) 12(7), 1051-1061. (Flow, functional studies) Immunology (1999) 96(1): 35-47. (functional studies)