Arcyriaflavin A
Arcyriaflavin A is a fungal metabolite obtained from the fungi, Nocardiopsis. Arcyriaflavin A is an inhibitor of CDK4 (IC50 = 140 nM) and CaMKII (IC50 = 25 nM) [1][2].
Product Specifications
CAS Number
118458-54-1
UNSPSC
12352005
Target
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/arcyriaflavin-a.html
Purity
99.8
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1NC(C2=C1C3=C(C4=C2C5=C(N4)C=CC=C5)NC6=C3C=CC=C6)=O
Molecular Formula
C20H11N3O2
Molecular Weight
325.32
References & Citations
[1]P A Horton, et al. Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian, Eudistoma sp. Experientia. 1994 Sep 15;50 (9) :843-5.|[2]Sanchez-Martinez C, et al. Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors. Bioorg Med Chem Lett. 2003 Nov 3;13 (21) :3835-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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