SPA4
SPA4 is a TLR4-interacting peptide. SPA4 inhibits the LPS-induced TNF-α cytokine response without effect the cell viability or size[1].
Product Specifications
CAS Number
1343908-95-1
UNSPSC
12352209
Target
Interleukin Related
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/spa4.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(N3[C@@H](CCC3)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN
Molecular Formula
C107H145N29O35
Molecular Weight
2397.47
References & Citations
[1]Shanjana Awasthi, et al. Mechanism of Anti-Inflammatory Activity of TLR4-Interacting SPA4 Peptide. Immunohorizons. 2021, 5, 8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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